Overview

  • Product nameAnti-EGR4 antibody
    See all EGR4 primary antibodies
  • Description
    Goat polyclonal to EGR4
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide:

    NCGSQGDYQAAPE

    , corresponding to internal sequence amino acids 218-230 of human EGR4 (NP_001956.2)

  • Positive control
    • Human brain (hippocampus, cerebellum and frontal cortex) lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab77342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesPeptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/4000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceEGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
    • Cellular localizationNuclear
    • Database links
    • Alternative names
      • AT133 antibody
      • Early growth response protein 4 antibody
      • Nerve growth factor induced clone C antibody
      • NGFI C antibody
      • NGFIC antibody
      • PAT133 antibody
      see all

    Anti-EGR4 antibody images

    • Anti-EGR4 antibody (ab77342) at 0.3 µg/ml + Human Brain (Hippocampus) lysate in RIPA buffer at 35 µg

      Predicted band size : 51 kDa
      Observed band size : 51 kDa

    References for Anti-EGR4 antibody (ab77342)

    ab77342 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77342.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"