Overview

  • Product nameAnti-eIF2A antibody
    See all eIF2A primary antibodies
  • Description
    Rabbit polyclonal to eIF2A
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 444-473 (UniProt ID: Q9BY44) of Human eIF2A conjugated to KLH.

  • Positive control
    • Ramos cell line lysates; Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab102786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 65 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionFunctions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
  • Tissue specificityWidely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
  • Sequence similaritiesBelongs to the WD repeat EIF2A family.
    Contains 3 WD repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • 65 kDa eukaryotic translation initiation factor 2A antibody
    • CDA 02 antibody
    • CDA02 antibody
    • EIF 2 antibody
    • EIF 2A antibody
    • eIF-2A antibody
    • EIF2 antibody
    • eif2a antibody
    • EIF2A_HUMAN antibody
    • Eukaryotic translation initiation factor 2A 65kDa antibody
    • Eukaryotic translation initiation factor 2A antibody
    • MST089 antibody
    • MSTP004 antibody
    • MSTP089 antibody
    see all

Anti-eIF2A antibody images

  • Anti-eIF2A antibody (ab102786) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 65 kDa
  • ab102786, at a 1/50 dilution, staining eIF2 in formalin fixed, paraffin embedded Human brain tissue by Immunohistochemistry, followed by peroxidase conjugated secondary antibody and DAB staining.

References for Anti-eIF2A antibody (ab102786)

ab102786 has not yet been referenced specifically in any publications.

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