• Product nameAnti-EIF3D antibody
    See all EIF3D primary antibodies
  • Description
    Rabbit polyclonal to EIF3D
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residues 200 and 250 of human EIF3D (NP_003744.1).

  • Positive control
    • HeLa and 293T whole cell lysates.


Associated products


Our Abpromise guarantee covers the use of ab85951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa).
  • Application notesIs unsuitable for IP.
  • Target

    • FunctionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
    • Sequence similaritiesBelongs to the eIF-3 subunit D family.
    • Post-translational
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • eIF 3 zeta antibody
      • eIF-3-zeta antibody
      • eIF3 p66 antibody
      • eIF3 zeta antibody
      • eIF3d antibody
      • EIF3D_HUMAN antibody
      • eIF3p66 antibody
      • EIF3S7 antibody
      • Eukaryotic translation initiation factor 3 subunit 7 antibody
      • Eukaryotic translation initiation factor 3 subunit 7 zeta 66/67kDa antibody
      • Eukaryotic translation initiation factor 3 subunit D antibody
      • MGC126526 antibody
      • MGC17258 antibody
      • OTTHUMP00000197900 antibody
      • OTTHUMP00000197901 antibody
      • Translation initiation factor eIF3 p66 subunit antibody
      see all

    Anti-EIF3D antibody images

    • All lanes : Anti-EIF3D antibody (ab85951) at 0.04 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg

      developed using the ECL technique

      Predicted band size : 64 kDa
      Observed band size : 64 kDa
      Additional bands at : 100 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 3 minutes

    References for Anti-EIF3D antibody (ab85951)

    ab85951 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab85951.
    Please use the links above to contact us or submit feedback about this product.