• Product nameAnti-eIF3e antibody
    See all eIF3e primary antibodies
  • Description
    Goat polyclonal to eIF3e
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Pig, Macaque Monkey
  • Immunogen

    Synthetic peptide:


    , corresponding to C terminal amino acids 425-436 of Human eIF3e according to NP_001559.1.

  • Positive control
    • Daudi cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab109589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).


  • FunctionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
  • Tissue specificityUbiquitously expressed. Expressed at highest levels in appendix, lymph, pancreas, skeletal muscle, spleen and thymus.
  • Sequence similaritiesBelongs to the eIF-3 subunit E family.
    Contains 1 PCI domain.
  • Post-translational
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Nucleus > PML body.
  • Information by UniProt
  • Database links
  • Alternative names
    • eIF-3 p48 antibody
    • eIF3e antibody
    • EIF3E_HUMAN antibody
    • EIF3S6 antibody
    • eIFe antibody
    • Eukaryotic translation initiation factor 3 subunit 6 antibody
    • Eukaryotic translation initiation factor 3 subunit E antibody
    • eukaryotic translation initiation factor 3, subunit 6 (48kD) antibody
    • INT6 antibody
    • mammary tumor-associated protein INT6 antibody
    • murine mammary tumor integration site 6 (oncogene homolog) antibody
    • Viral integration site protein INT-6 homolog antibody
    see all

Anti-eIF3e antibody images

References for Anti-eIF3e antibody (ab109589)

ab109589 has not yet been referenced specifically in any publications.

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