• Product nameAnti-eIF3e antibody
    See all eIF3e primary antibodies
  • Description
    Rabbit polyclonal to eIF3e
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 360 - 409 (LNMTPEEAER WIVNLIRNAR LDAKIDSKLG HVVMGNNAVS PYQQVIEKTK) of Human eIF3e (NP_001559)

  • Positive control
    • HepG2 cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab85397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
  • Tissue specificityUbiquitously expressed. Expressed at highest levels in appendix, lymph, pancreas, skeletal muscle, spleen and thymus.
  • Sequence similaritiesBelongs to the eIF-3 subunit E family.
    Contains 1 PCI domain.
  • Post-translational
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Nucleus > PML body.
  • Information by UniProt
  • Database links
  • Alternative names
    • eIF-3 p48 antibody
    • eIF3e antibody
    • EIF3E_HUMAN antibody
    • EIF3S6 antibody
    • eIFe antibody
    • Eukaryotic translation initiation factor 3 subunit 6 antibody
    • Eukaryotic translation initiation factor 3 subunit E antibody
    • eukaryotic translation initiation factor 3, subunit 6 (48kD) antibody
    • INT6 antibody
    • mammary tumor-associated protein INT6 antibody
    • murine mammary tumor integration site 6 (oncogene homolog) antibody
    • Viral integration site protein INT-6 homolog antibody
    see all

Anti-eIF3e antibody images

  • Anti-eIF3e antibody (ab85397) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 52 kDa

References for Anti-eIF3e antibody (ab85397)

ab85397 has not yet been referenced specifically in any publications.

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