Overview

  • Product name
    Anti-eIF3K antibody [2313C2a]
    See all eIF3K primary antibodies
  • Description
    Mouse monoclonal [2313C2a] to eIF3K
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human EIF3S12

  • Positive control
    • Recombinant human EIF3S12

Properties

Applications

Our Abpromise guarantee covers the use of ab50736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 25 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • Tissue specificity
    Ubiquitous, with the highest levels of expression in brain, testis and kidney.
  • Sequence similarities
    Belongs to the eIF-3 subunit K family.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARG134 antibody
    • eIF 3 p25 antibody
    • eIF 3 p28 antibody
    • eIF-3 p25 antibody
    • eIF-3 p28 antibody
    • EIF3-p28 antibody
    • eif3k antibody
    • EIF3K_HUMAN antibody
    • EIF3S12 antibody
    • Eukaryotic translation initiation factor 3 subunit 12 antibody
    • Eukaryotic translation initiation factor 3 subunit K antibody
    • HSPC029 antibody
    • M9 antibody
    • MSTP001 antibody
    • Muscle specific gene M9 protein antibody
    • Muscle-specific gene M9 protein antibody
    • PLAC 24 antibody
    • PLAC-24 antibody
    • PLAC24 antibody
    • PRO1474 antibody
    • PTD001 antibody
    see all

Images

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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