Overview

  • Product nameAnti-eIF3K antibody
    See all eIF3K primary antibodies
  • Description
    Rabbit polyclonal to eIF3K
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to an internal region of Human eIF3K.

  • Positive control
    • HeLa cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab92740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: 1/40000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 25 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
    • Tissue specificityUbiquitous, with the highest levels of expression in brain, testis and kidney.
    • Sequence similaritiesBelongs to the eIF-3 subunit K family.
    • Cellular localizationNucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARG134 antibody
      • eIF 3 p25 antibody
      • eIF 3 p28 antibody
      • eIF-3 p25 antibody
      • eIF-3 p28 antibody
      • EIF3-p28 antibody
      • eif3k antibody
      • EIF3K_HUMAN antibody
      • EIF3S12 antibody
      • Eukaryotic translation initiation factor 3 subunit 12 antibody
      • Eukaryotic translation initiation factor 3 subunit K antibody
      • HSPC029 antibody
      • M9 antibody
      • MSTP001 antibody
      • Muscle specific gene M9 protein antibody
      • Muscle-specific gene M9 protein antibody
      • PLAC 24 antibody
      • PLAC-24 antibody
      • PLAC24 antibody
      • PRO1474 antibody
      • PTD001 antibody
      see all

    Anti-eIF3K antibody images

    • All lanes : Anti-eIF3K antibody (ab92740) at 1/500 dilution

      Lane 1 : HeLa cell extract
      Lane 2 : HeLa cell extract with blocking peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 25 kDa

    References for Anti-eIF3K antibody (ab92740)

    ab92740 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"