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Rabbit polyclonal to EIF3S2
Predicted to work with:
Mouse, Rat, Rabbit, Chicken, Cow, Xenopus laevis, Xenopus tropicalis
Recombinant fragment corresponding to a region within amino acids 66-325 of Human EIF3S2 (Uniprot ID: Q13347).
A431, H1299, HeLa and HepG2 whole cell lysates. HeLa cells.
Keep as concentrated solution.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 37 kDa.
1/100 - 1/1000.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Belongs to the eIF-3 subunit I family.
Contains 5 WD repeats.
Phosphorylated by TGF-beta type II receptor.
Information by UniProt
eIF3 beta antibody
eIF3 p36 antibody
Western blot - Anti-EIF3S2 antibody (ab155477)
All lanes : Anti-EIF3S2 antibody (ab155477) at 1/1000 dilution Lane 1 : A431 whole cell lysate Lane 2 : H1299 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 37 kDa 10% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-EIF3S2 antibody (ab155477)
Immunofluorescence analysis of methanol-fixed HeLa cells, labeling EIF3S2 using ab155477 at a 1/200 dilution. The image in the lower panel was costained with Hoechst 33342.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"