Overview

  • Product nameAnti-EIF3S2 antibody
    See all EIF3S2 primary antibodies
  • Description
    Chicken polyclonal to EIF3S2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide, corresponding to N terminal amino acids 1-230 of Human EIF3S2.

Properties

Applications

Our Abpromise guarantee covers the use of ab37526 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
ELISA Use a concentration of 1 µg/ml.

Target

  • FunctionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • Sequence similaritiesBelongs to the eIF-3 subunit I family.
    Contains 5 WD repeats.
  • Post-translational
    modifications
    Phosphorylated by TGF-beta type II receptor.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • eIF-3-beta antibody
    • eIF3 beta antibody
    • eIF3 p36 antibody
    • eIF3-beta antibody
    • eIF3-p36 antibody
    • eIF3i antibody
    • EIF3I_HUMAN antibody
    • EIF3S2 antibody
    • EIF3S2, formerly antibody
    • Eukaryotic translation initiation factor 3 subunit 2 antibody
    • Eukaryotic translation initiation factor 3 subunit 2 beta antibody
    • Eukaryotic translation initiation factor 3 subunit I antibody
    • eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody
    • eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa antibody
    • eukaryotic translation initiation factor 3, subunit 2, formerly antibody
    • eukaryotic translation initiation factor 3, subunit I antibody
    • Predicted protein of HQ2242 antibody
    • PRO2242 antibody
    • TGF beta receptor interacting protein 1 antibody
    • TGF-beta receptor-interacting protein 1 antibody
    • TGFbeta receptor interacting protein 1 antibody
    • TGFbeta receptor-interacting protein 1 antibody
    • TRIP 1 antibody
    • TRIP-1 antibody
    • TRIP1 antibody
    see all

Anti-EIF3S2 antibody images

  • Direct ELISA test. Serial dilutions of Human EIF3S2 protein were used as test antigen. ab37526 was used as test antibody at 1µg/ml. Goat anti-IgY-HRP was used as secondary antibody.
  • Anti-EIF3S2 antibody (ab37526) at 1/2000 dilution + E. coli derived fusion protein at 2.5 µg

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

References for Anti-EIF3S2 antibody (ab37526)

This product has been referenced in:
  • Angelucci S  et al. Proteome analysis of human Wharton's jelly cells during in vitro expansion. Proteome Sci 8:18 (2010). WB ; Human . Read more (PubMed: 20346146) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab37526.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"