• Product nameAnti-eIF5A antibody
    See all eIF5A primary antibodies
  • Description
    Goat polyclonal to eIF5A
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide to the N terminal region of Human eIF5A.
    (NP_001137233.1, NP_001961.1 and NP_001137234.1)

  • Positive control
    • Human Vessel, Spleen, Tonsil tissues and MOLT4 lysate



Our Abpromise guarantee covers the use of ab119115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 17 kDa.
IHC-P Use a concentration of 3.75 µg/ml.


  • FunctionmRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
  • Tissue specificityExpressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).
  • Sequence similaritiesBelongs to the eIF-5A family.
  • Post-translational
    eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).
  • Cellular localizationCytoplasm. Nucleus. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
  • Information by UniProt
  • Database links
  • Alternative names
    • eIF 4D antibody
    • eIF 5A 1 antibody
    • EIF 5A antibody
    • eIF 5A1 antibody
    • eIF-4D antibody
    • eIF-5A antibody
    • eIF-5A-1 antibody
    • eIF-5A1 antibody
    • eIF4D antibody
    • eif5a antibody
    • EIF5A1 antibody
    • eIF5AI antibody
    • Eukaryotic initiation factor 5A antibody
    • Eukaryotic initiation factor 5A isoform 1 antibody
    • Eukaryotic translation initiation factor 5A 1 antibody
    • Eukaryotic translation initiation factor 5A antibody
    • Eukaryotic translation initiation factor 5A-1 antibody
    • IF5A1_HUMAN antibody
    • MGC104255 antibody
    • MGC99547 antibody
    • Rev binding factor antibody
    • Rev-binding factor antibody
    • uORF A antibody
    • uORF antibody
    see all

Anti-eIF5A antibody images

  • Anti-eIF5A antibody (ab119115) at 0.1 µg/ml (incubated for 1 hour ) + MOLT4 lysate in RIPA buffer at 35 µg
    developed using the ECL technique

    Predicted band size : 17 kDa
  • Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Human Vessel tissue using ab119115 at 3.75 µg/ml.
  • Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Human Spleen tissue using ab119115 at 3.75 µg/ml.
  • Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Human Tonsil tissue using ab119115 at 3.75 µg/ml.

References for Anti-eIF5A antibody (ab119115)

ab119115 has not yet been referenced specifically in any publications.

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