Overview

  • Product nameAnti-EIF5AL1 antibody
  • Description
    Rabbit polyclonal to EIF5AL1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 101-130 of Human EIF5AL1 (NP_001093162.1)

  • Positive control
    • Ramos cell line lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab110502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 17 kDa.

Target

  • FunctionmRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
  • Sequence similaritiesBelongs to the eIF-5A family.
  • Post-translational
    modifications
    eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).
  • Cellular localizationCytoplasm. Nucleus. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
  • Information by UniProt
  • Database links
  • Alternative names
    • bA342M3.3 antibody
    • eIF-5A-1-like antibody
    • eIF-5A1-like antibody
    • EIF5AL1 antibody
    • EIF5AP1 antibody
    • Eukaryotic initiation factor 5A isoform 1-like antibody
    • Eukaryotic translation initiation factor 5A-1-like antibody
    • IF5AL_HUMAN antibody
    • RP11-342M3.3 antibody
    see all

Anti-EIF5AL1 antibody images

  • Anti-EIF5AL1 antibody (ab110502) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 17 kDa

References for Anti-EIF5AL1 antibody (ab110502)

ab110502 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"