• Product name
  • Description
    Rabbit polyclonal to ELAC2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-826 of Human ELAC2 (NP_060597.3).

  • Positive control
    • Human liver tissue lysate; ELAC2 transfected 293T cell line lysate



Our Abpromise guarantee covers the use of ab103793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 92 kDa.


  • Function
    Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
  • Tissue specificity
    Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
  • Involvement in disease
    Defects in ELAC2 may be a cause of susceptibility to prostate cancer (PC) [MIM:176807]. It is a malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
  • Sequence similarities
    Belongs to the RNase Z family.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • COXPD17 antibody
    • elaC homolog 2 (E. coli) antibody
    • ElaC homolog protein 2 antibody
    • elaC ribonuclease Z 2 antibody
    • elaC, E. coli, homolog of, 2 antibody
    • ELAC2 antibody
    • ELC2 antibody
    • FLJ10530 antibody
    • FLJ36693 antibody
    • FLJ42848 antibody
    • Heredity prostate cancer protein 2 antibody
    • HPC2 antibody
    • putative prostate cancer susceptibility protein HPC2/ELAC2 antibody
    • Ribonuclease Z 2 antibody
    • Ribonuclease Z, long form antibody
    • Ribonuclease Z2 antibody
    • RNase Z 2 antibody
    • RNase Z2 antibody
    • RNase ZL antibody
    • RNZ2_HUMAN antibody
    • tRNA 3 endonuclease 2 antibody
    • tRNase Z (long form) antibody
    • tRNase Z 2 antibody
    • tRNase Z2 antibody
    • Zinc phosphodiesterase ELAC protein 2 antibody
    see all

Anti-ELAC2 antibody images

  • Anti-ELAC2 antibody (ab103793) at 5 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 92 kDa
  • All lanes : Anti-ELAC2 antibody (ab103793) at 5 µg/ml

    Lane 1 : ELAC2 transfected 293T cell lysate
    Lane 2 : 293T non-transfected cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 92 kDa

References for Anti-ELAC2 antibody (ab103793)

ab103793 has not yet been referenced specifically in any publications.

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