Overview

  • Product nameAnti-Elafin/Skalp antibody
    See all Elafin/Skalp primary antibodies
  • Description
    Rabbit polyclonal to Elafin/Skalp
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Chimpanzee
  • Immunogen

    Synthetic peptide within residues: KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM , corresponding to internal sequence amino acids 36-85 of Human Elafin/Skalp (NP_002629)

  • Positive control
    • 721_B cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 6 kDa (predicted molecular weight: 6 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNeutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis.
  • Sequence similaritiesContains 1 WAP domain.
  • DomainConsists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cementoin antibody
    • ELAF_HUMAN antibody
    • Elafin antibody
    • Elastase Specific Inhibitor antibody
    • Elastase-specific inhibitor antibody
    • ES 1 antibody
    • ESI antibody
    • Peptidase inhibitor 3 antibody
    • Peptidase inhibitor 3, skin derived antibody
    • PI 3 antibody
    • PI-3 antibody
    • PI3 antibody
    • Pre elafin antibody
    • Protease inhibitor 3 skin derived antibody
    • Protease inhibitor 3, skin derived (SKALP) antibody
    • Protease inhibitor WAP3 antibody
    • SKALP antibody
    • Skin derived Anti leukoproteinase antibody
    • Skin-derived antileukoproteinase antibody
    • Trappin 2 antibody
    • WAP four disulfide core domain 14 antibody
    • WAP four disulfide core domain protein 14 antibody
    • WAP four-disulfide core domain protein 14 antibody
    • WAP3 antibody
    • WFDC14 antibody
    see all

Anti-Elafin/Skalp antibody images

  • Anti-Elafin/Skalp antibody (ab85187) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 6 kDa
    Observed band size : 6 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Elafin/Skalp antibody (ab85187)

ab85187 has not yet been referenced specifically in any publications.

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