Overview

  • Product name
    Ellagic acid
  • Description
    Selective, casein kinase 2 (CK2) inhibitor
  • Biological description
    Selective, ATP-competitive casein kinase 2 (CK2) inhibitor (Ki = 20 nM). Exhibits a multitude of biological activities including antioxidant, antiproliferative and pro-apoptotic activity.
  • Purity
    > 99%

Properties

  • Chemical name
    2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • Molecular weight
    302.20
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C14H6O8
  • CAS Number
    476-66-4
  • Storage instructions
    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview
    Soluble in DMSO to 1 mM and in ethanol to 1 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Tree bark

  • Research areas

    References for Ellagic acid (ab120622)

    This product has been referenced in:
    • Cozza G  et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006). Read more (PubMed: 16610779) »
    • Seeram NP  et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-7 (2005). Read more (PubMed: 15936648) »
    • Han DH  et al. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res 26:3601-6 (0). Read more (PubMed: 17094489) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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