Overview

  • Product nameEllagic acid
  • Description
    Selective, casein kinase 2 (CK2) inhibitor
  • Biological descriptionSelective, ATP-competitive casein kinase 2 (CK2) inhibitor (Ki = 20 nM). Exhibits a multitude of biological activities including antioxidant, antiproliferative and pro-apoptotic activity.
  • Purity> 99%

Properties

  • Chemical name2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • Molecular weight302.20
  • Chemical structureChemical Structure
  • Molecular formulaC14H6O8
  • CAS Number476-66-4
  • Storage instructionsStore at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under Desiccating conditions.
  • Solubility overviewSoluble in DMSO to 1 mM and in ethanol to 1 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Tree bark

  • Research areas

    References for Ellagic acid (ab120622)

    This product has been referenced in:
    • Cozza G  et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006). Read more (PubMed: 16610779) »
    • Seeram NP  et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-7 (2005). Read more (PubMed: 15936648) »
    • Han DH  et al. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res 26:3601-6 (0). Read more (PubMed: 17094489) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"