Recombinant
RabMAb

Anti-Ellis van Creveld syndrome antibody [EPR10408] (ab171952)

Overview

  • Product name
    Anti-Ellis van Creveld syndrome antibody [EPR10408]
  • Description
    Rabbit monoclonal [EPR10408] to Ellis van Creveld syndrome
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Ellis van Creveld syndrome aa 200-300 (Cysteine residue). The exact sequence is proprietary.
    Database link: P57679

  • Positive control
    • MCF7, K562, HeLa and 293T cell lysates. HeLa cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab171952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 112 kDa.
ICC/IF 1/50 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Relevance
      Ellis van Creveld syndrome is an autosomal recessive disorder characterized by the clinical tetrad of chondrodystrophy, polydactyly, ectodermal dysplasia and cardiac anomalies. Patients manifest short limb dwarfism, short ribs, postaxial polydactyly and dysplastic nails and teeth. Congenital heart defects, most commonly an atrioventricular septal defect, are observed in 60% of affected individuals. Defects in this protein are a cause of Ellis van Creveld syndrome (EVC).
    • Cellular localization
      Membrane; Single pass membrane protein
    • Database links
    • Alternative names
      • DWF 1 antibody
      • DWF1 antibody
      • Ellis van Creveld syndrome protein antibody
      • EVC antibody
      • EVC1 antibody
      • EVCL antibody
      • MGC105107 antibody
      see all

    Images

    • All lanes : Anti-Ellis van Creveld syndrome antibody [EPR10408] (ab171952) at 1/1000 dilution

      Lane 1 : MCF7 cell lysate
      Lane 2 : K562 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 112 kDa

    • Immunofluorescent analysis of HeLa cells labeling Ellis van Creveld syndrome  with ab171952 at 1/50 dilution (red). DAPI nuclear staining (blue).

    References

    ab171952 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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