Overview

  • Product nameAnti-ELMO2 antibody
    See all ELMO2 primary antibodies
  • Description
    Goat polyclonal to ELMO2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide:C-

    PKEPSSYDFVYHYG

    (with a Cysteine residue linker), corresponding to C terminal amino acids 707-720 of Human ELMO2

  • Positive control
    • Human brain lysate Human prostate tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab113976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 83 kDa.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInvolved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • Tissue specificityWidely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • Sequence similaritiesContains 1 ELMO domain.
    Contains 1 PH domain.
  • Cellular localizationCytoplasm. Cytoplasm > cytosol. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CED 12 antibody
    • Ced 12 homolog 2 antibody
    • CED 12 homolog A antibody
    • CED 12A antibody
    • CED-12 antibody
    • ced-12 homolog 2 antibody
    • CED12 antibody
    • CED12 homolog A antibody
    • CED12, C. elegans, homolog of, 2 antibody
    • CED12A antibody
    • ELMO 2 antibody
    • ELMO-2 antibody
    • ELMO2 antibody
    • ELMO2_HUMAN antibody
    • Engulfment and cell motility 2 (ced 12 homolog, C. elegans) antibody
    • Engulfment and cell motility 2 antibody
    • Engulfment and cell motility gene 2 antibody
    • Engulfment and cell motility protein 2 antibody
    • FLJ11656 antibody
    • hCED 12A antibody
    • hCED-12A antibody
    • hCED12A antibody
    • KIAA1834 antibody
    • OTTHUMP00000031762 antibody
    • PH domain protein CED12A antibody
    • Protein ced 12 homolog A antibody
    • Protein ced-12 homolog A antibody
    see all

Anti-ELMO2 antibody images

  • Anti-ELMO2 antibody (ab113976) at 2 µg/ml + Human brain lysate in RIPA buffer at 30 µg

    Predicted band size : 83 kDa
  • ab113976, at 3.75 µg/ml, staining ELMO2 in formalin fixed paraffin embedded Human prostate by Immunohistochemistry.

References for Anti-ELMO2 antibody (ab113976)

ab113976 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"