Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab2271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 81 kDa).

Target

  • FunctionInvolved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • Sequence similaritiesContains 1 ELMO domain.
    Contains 1 PH domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CED 12 antibody
    • Ced 12 homolog 3 antibody
    • CED12 antibody
    • ELMO 3 antibody
    • ELMO3 antibody
    • ELMO3_HUMAN antibody
    • Engulfment and cell motility 3 antibody
    • Engulfment and cell motility protein 3 antibody
    • FLJ13824 antibody
    see all

Anti-ELMO3 antibody images

References for Anti-ELMO3 antibody (ab2271)

ab2271 has not yet been referenced specifically in any publications.

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Thank you for contacting Abcam regarding our ELMO3 antibodies ab76402 and ab2271. I have reviewed the datasheets for both of these products and the information regarding the molecular weights of these proteins. According to SwissProt, there are three i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"