• Product name
  • Description
    Rabbit polyclonal to ELOVL6
  • Host species
  • Tested applications
    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 16 amino acid peptide near the carboxy terminus of the human ELOVL6 (GenBank accession no. NP_076995).

  • Positive control
    • Human brain tissue lysate.



Our Abpromise guarantee covers the use of ab69857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 1 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 31 kDa).Can be blocked with ELOVL6 peptide (ab114079).


  • Function
    Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs.
  • Tissue specificity
  • Sequence similarities
    Belongs to the ELO family.
  • Post-translational
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-keto acyl-CoA synthase ELOVL6 antibody
    • Elongation of very long chain fatty acids protein 6 antibody
    • ELOV6_HUMAN antibody
    • ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3 like, yeast) antibody
    • ELOVL fatty acid elongase 6 antibody
    • ELOVL6 antibody
    • FACE antibody
    • FAE antibody
    • Fatty acid elongase 2 antibody
    • Fatty acyl CoA elongase antibody
    • Fatty acyl-CoA elongase antibody
    • FLJ23378 antibody
    • hELO2 antibody
    • LCE antibody
    • Long chain fatty acyl elongase antibody
    • Long-chain fatty-acyl elongase antibody
    • MGC5487 antibody
    • Myelin associated SUR4 protein antibody
    see all


  • Lane 1 : Anti-ELOVL6 antibody (ab69857) at 1 µg/ml
    Lane 2 : Anti-ELOVL6 antibody (ab69857) at 2 µg/ml

    All lanes : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 31 kDa
    Observed band size: 28 kDa (why is the actual band size different from the predicted?)

  • Immunohistochemistry of ELOVL6 in human brain with ab69857 at 5 µg/ml.
  • ICC/IF image of ab69857 stained PC12 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab69857, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

  • Immunofluorescence of ELOVL6 in Human Brain cells using ab69857 at 20 ug/ml.


This product has been referenced in:
  • Ducheix S  et al. Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling. PLoS One 12:e0181393 (2017). Read more (PubMed: 28732092) »
  • Shinohara S  et al. Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes. Int J Mol Med 38:574-84 (2016). Read more (PubMed: 27353085) »

See all 5 Publications for this product

Customer reviews and Q&As

Thank you very much for your call today and for letting us know about the trouble with this antibody.

As we discussed, I'm sending a free of charge replacement vial on the order *** which should arrive tomorrow.

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