Overview

  • Product name
    Anti-ELYS antibody [2318C1a]
    See all ELYS primary antibodies
  • Description
    Mouse monoclonal [2318C1a] to ELYS
  • Tested applications
    Suitable for: Dot blot, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment

Properties

Applications

Our Abpromise guarantee covers the use of ab53540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 253 kDa.

Target

  • Function
    Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
  • Sequence similarities
    Belongs to the ELYS family.
    Contains 1 A.T hook DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus matrix. Chromosome > centromere > kinetochore. Nucleus > nucleoplasm. Nucleus > nuclear pore complex. Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.
  • Information by UniProt
  • Database links
  • Form
    There are 2 isoforms produced by alternative splicing.
  • Alternative names
    • ahctf1 antibody
    • AT hook containing transcription factor 1 antibody
    • DKFZp434N093 antibody
    • ELYS antibody
    • ELYS transcription factor like protein TMBS62 antibody
    • ELYS_HUMAN antibody
    • Embryonic large molecule derived from yolk sac antibody
    • MST108 antibody
    • MSTP108 antibody
    • Protein ELYS antibody
    • Protein MEL-28 antibody
    • Putative AT-hook-containing transcription factor 1 antibody
    • TMBS62 antibody
    see all

Images

References

ab53540 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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