Anti-EMR2 antibody (ab75190)
Key features and details
- Rabbit polyclonal to EMR2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-EMR2 antibody -
Description
Rabbit polyclonal to EMR2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide derived from an internal region of human EMR2
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Positive control
- HeLa cell extract
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab75190 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab75190 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 91 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 91 kDa. |
Target
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Function
Receptor probably involved in cell attachment. -
Tissue specificity
Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 5 EGF-like domains.
Contains 1 GPS domain. -
Domain
The GPS domain is necessary, but not sufficient for receptor cleavage, which require the entire extracellular stalk.
Binding to chondroitin sulfate is mediated by the fourth EGF domain. -
Post-translational
modificationsAutoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 30817 Human
- Omim: 606100 Human
- SwissProt: Q9UHX3 Human
- Unigene: 531619 Human
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Alternative names
- CD 312 antibody
- CD 312 antigen antibody
- CD312 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab75190 has not yet been referenced specifically in any publications.