Overview

  • Product nameAnti-EMR3 antibody
    See all EMR3 primary antibodies
  • Description
    Rabbit polyclonal to EMR3
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the C-terminal of human EMR3.

  • Positive control
    • Extracts from Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab75283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 73 kDa.
ELISA 1/10000.

Target

  • RelevanceEMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
  • Cellular localizationCell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected.
  • Database links
  • Alternative names
    • Egf like module containing mucin like hormone receptor like 3 antibody
    • Egf like module containing mucin like receptor 3 antibody
    • EGF like module containing mucin like receptor EMR3 antibody
    • EMR 3 antibody

Anti-EMR3 antibody images

  • All lanes : Anti-EMR3 antibody (ab75283) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 73 kDa
    Observed band size : 73 kDa
    Additional bands at : 30 kDa,40 kDa,45 kDa. We are unsure as to the identity of these extra bands.

References for Anti-EMR3 antibody (ab75283)

ab75283 has not yet been referenced specifically in any publications.

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