Overview

  • Product nameAnti-EMX2 antibody [4F7]
    See all EMX2 primary antibodies
  • Description
    Mouse monoclonal [4F7] to EMX2
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog
  • Immunogen

    Recombinant fragment: HSPHPLFASQ QRDPSTFYPW LIHRYRYLGH RFQGNDTSPE SFLLHNAL A RKPKRIRTAF SPSQLLRLEH AFEKNHYVVG AERKQLAHSL SLTETQVKVW, corresponding to amino acids 103-201 of Human EMX2 with a proprietary tag (NP_004089).

  • Positive control
    • Human Brain cortex and Human Skeletal muscle tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionTranscription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
  • Tissue specificityCerebral cortex.
  • Involvement in diseaseDefects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
  • Sequence similaritiesBelongs to the EMX homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Empty spiracles homeobox 2 antibody
    • Empty spiracles homolog 2 (Drosophila) antibody
    • Empty spiracles homolog 2 antibody
    • Empty spiracles like protein 2 antibody
    • Empty spiracles-like protein 2 antibody
    • EMX 2 antibody
    • EMX2 antibody
    • EMX2_HUMAN antibody
    • Homeobox protein EMX 2 antibody
    • Homeobox protein EMX2 antibody
    see all

Anti-EMX2 antibody [4F7] images

  • ab110994, at 5µg/ml, staining EMX2 in formalin-fixed, paraffin-embedded Human Brain cortex by Immunohistochemistry.
  • ab110994, at 5µg/ml, staining EMX2 in formalin-fixed, paraffin-embedded Human skeletal muscle by Immunohistochemistry.

References for Anti-EMX2 antibody [4F7] (ab110994)

ab110994 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"