Overview

  • Product nameAnti-ENC1 antibody
    See all ENC1 primary antibodies
  • Description
    Rabbit polyclonal to ENC1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (SVSVHENRKS RASSGSINIY LFHKSSYADS VLTHLNLLRQ QRLFTDVLLH) of Human ENC1 (NP_003624).

  • Positive control
    • ACHN cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 66 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionActin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • Tissue specificityDetected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • Developmental stageDramatically up-regulated upon neuronal differentiation.
  • Post-translational
    modifications
    Ubiquitinated and probably targeted for proteasome-independent degradation.
  • Cellular localizationNucleus matrix. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCL 28 antibody
    • CCL28 antibody
    • Ectoderm neural cortex protein 1 antibody
    • Ectoderm-neural cortex protein 1 antibody
    • Ectodermal neural cortex (with BTB like domain) antibody
    • ENC 1 antibody
    • ENC-1 antibody
    • ENC1 antibody
    • ENC1_HUMAN antibody
    • FLJ39259 antibody
    • Kelch like 35 antibody
    • Kelch like 37 antibody
    • Kelch-like protein 37 antibody
    • KLHL 35 antibody
    • KLHL35 antibody
    • KLHL37 antibody
    • NRPB antibody
    • Nuclear matrix protein NRP/B antibody
    • Nuclear restricted protein BTB domain like (brain) antibody
    • OTTHUMP00000128235 antibody
    • OTTHUMP00000222054 antibody
    • p53 induced gene 10 protein antibody
    • p53-induced gene 10 protein antibody
    • PIG 10 antibody
    • PIG10 antibody
    • TP53I10 antibody
    • Tumor protein p53 inducible protein 10 antibody
    see all

Anti-ENC1 antibody images

  • Anti-ENC1 antibody (ab94561) at 1 µg/ml (in 5% skim milk / PBS buffer) + ACHN cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 66 kDa

References for Anti-ENC1 antibody (ab94561)

ab94561 has not yet been referenced specifically in any publications.

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