Anti-Endomorphin 1 antibody (ab10285)

Overview

  • Product nameAnti-Endomorphin 1 antibody
    See all Endomorphin 1 primary antibodies
  • Description
    Rabbit polyclonal to Endomorphin 1
  • SpecificitySensitivity has been determined by ELISA. Less than 1ng of antibody could be detected after binding to Endomorphin 1 which is conjugated to titer plate: Endomorphin 1 = 100 Endomorphin 2 = 5 Leu5-Enkephalin = <0.01 Met5-Enkephalin = <0.03 beta-Endorphin = <0.01
  • Tested applicationsSuitable for: IHC-Fr, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Pig, Monkey
  • Immunogen

    Synthetic peptide conjugated to BSA.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesSelectivity towards Endomorphin 1 has been achieved by separating fraction of affinity purified antibodies which did not bind to Endomorphin 2.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab10285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 15 µg/ml.
ELISA Use at an assay dependent concentration.

Target

  • RelevanceThe endogenous agonists for the mu-opiate receptors, endomorphin-1; Tyr-Pro-Trp-Phe-NH2, and endomorphin-2; Tyr-Pro-Phe-Phe-NH2 have been reported to show hypotensive activity and Ca2+ channel current inhibitory activity [Biochem. Biophys. Res. Commun.,235, 567 (1997)]. Although first identified in bovine brain, it is thought that endomorphin-1 and 2 are common mu-opiate agonists in mammals, including humans. Endomorphins may be useful for the study of pain perception together with some other biological functions in the body.
  • Alternative names
    • EM 1 antibody

Anti-Endomorphin 1 antibody images

  • ab10285 staining Endomorphin 1 in rat Peryaqueductal Grey Matter by Immunohistochemistry (PFA perfusion fixed frozen sections).

References for Anti-Endomorphin 1 antibody (ab10285)

ab10285 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Endomorphins are 4-amino-acid peptides with molecular weight ~ 480 Daltons. Peptides with such a small weight cannot be run by western blotting - there is no such a gel that would allow retain such small peptides. Secon...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"