Anti-Endomucin antibody [TX18] (Biotin) (ab45772)

Overview

  • Product name
    Anti-Endomucin antibody [TX18] (Biotin)
    See all Endomucin primary antibodies
  • Description
    Rat monoclonal [TX18] to Endomucin (Biotin)
  • Conjugation
    Biotin
  • Specificity
    This antibody is specific for Endomucin.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Endomucin protein (Human)

  • Positive control
    • BW5147 cell lines
  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

Properties

Applications

Our Abpromise guarantee covers the use of ab45772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10.

Target

  • Function
    Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
  • Tissue specificity
    Expressed in heart, kidney and lung.
  • Post-translational
    modifications
    Highly O-glycosylated. Sialic acid-rich glycoprotein.
  • Cellular localization
    Secreted and Cell membrane. Membrane. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
  • Information by UniProt
  • Database links
  • Alternative names
    • EMCN antibody
    • EMCN2 antibody
    • Endomucin 2 antibody
    • Endomucin antibody
    • Endomucin-2 antibody
    • Endothelial sialomucin antibody
    • Gastric cancer antigen Ga34 antibody
    • MUC-14 antibody
    • MUC14 antibody
    • MUCEN_HUMAN antibody
    • Mucin 14 antibody
    • Mucin-14 antibody
    see all

Images

  • Detection of Endomucin in BW5147 cell lines. Cells were stained using 1/10 biotin conjugated anti human-Endomucin antibody ab45772 and streptavidin-FITC (blue) or streptavidin-FITC alone (red).

References

This product has been referenced in:
  • Liang C  et al. MicroRNA-18a-5p functions as an oncogene by directly targeting IRF2 in lung cancer. Cell Death Dis 8:e2764 (2017). IF ; Mouse . Read more (PubMed: 28471447) »

See 1 Publication for this product

Customer reviews and Q&As



I have contacted the lab who have confirmed that the BW5147 cells used in this experiment were transfected with human Endomucin.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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