Overview

  • Product nameAnti-Endonuclease V antibody
  • Description
    Rabbit polyclonal to Endonuclease V
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Horse, Cow, Cat, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 138-187 (VACHLGVLTE LPCIGVAKKL LQVDGLENNA LHKEKIVLLQ AGGDTFPLIG) of Mouse Endonuclease V (isoform 1, NP_001158108).

  • Positive control
    • Mouse brain lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab125517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSelectively cleaves DNA at the second phosphodiester bond 3' to hypoxanthine- and uracil-containing nucleotides. Shows higher activity towards single-stranded than double-stranded DNA and towards hypoxanthine than uracil.
  • Tissue specificityHighest levels detected in liver with high levels also found in heart, kidney and testis. Expressed at low levels in brain.
  • Sequence similaritiesBelongs to the endonuclease V family.
  • Information by UniProt
  • Database links
  • Alternative names
    • A730011L01Rik antibody
    • Endonuclease V antibody
    • ENDOV antibody
    • ENDOV_MOUSE antibody

Anti-Endonuclease V antibody images

  • Anti-Endonuclease V antibody (ab125517) at 1 µg/ml + Mouse brain lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 37 kDa

References for Anti-Endonuclease V antibody (ab125517)

ab125517 has not yet been referenced specifically in any publications.

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