Overview

  • Product nameAnti-ENO3 antibody
    See all ENO3 primary antibodies
  • Description
    Rabbit polyclonal to ENO3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, surrounding amino acids 49-53 (L-R-D-G-D) of Human ENO3.

  • Positive control
    • 3T3, HepG2 and C2C12 cell extracts.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab119327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.

Target

  • FunctionAppears to have a function in striated muscle development and regeneration.
  • Tissue specificityThe alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • PathwayCarbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
  • Involvement in diseaseDefects in ENO3 are the cause of glycogen storage disease type 13 (GSD13) [MIM:612932]. A metabolic disorder that results in exercise-induced myalgias, generalized muscle weakness and fatigability. It is characterized by increased serum creatine kinase and decreased enolase 3 activity. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected on ultrastructural analysis.
  • Sequence similaritiesBelongs to the enolase family.
  • Developmental stageDuring ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
  • Cellular localizationCytoplasm. Localized to the Z line. Some colocalization with CKM at M-band.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2 phospho D glycerate hydrol yase antibody
    • 2 phospho D glycerate hydrolyase antibody
    • 2-phospho-D-glycerate hydro-lyase antibody
    • Beta enolase antibody
    • Beta-enolase antibody
    • ENO3 antibody
    • ENOB_HUMAN antibody
    • Enolase 3 (beta muscle) antibody
    • Enolase 3 antibody
    • Enolase3 antibody
    • GSD13 antibody
    • MSE antibody
    • Muscle specific enolase antibody
    • Muscle-specific enolase antibody
    • Skeletal muscle enolase antibody
    see all

Anti-ENO3 antibody images

  • All lanes : Anti-ENO3 antibody (ab119327) at 1/500 dilution

    Lane 1 : 3T3 cell extract
    Lane 2 : HepG2 cell extract
    Lane 3 : C2C12 cell extract


    Predicted band size : 47 kDa

References for Anti-ENO3 antibody (ab119327)

ab119327 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119327.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"