Overview

  • Product nameAnti-ENOX2 antibody
    See all ENOX2 primary antibodies
  • Description
    Rabbit polyclonal to ENOX2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide, corresponding to N terminal amino acids 155-204 (YRIRLGSSTD KKDTGRLHVD FAQARDDLYE WECKQRMLAR EERHRRRMEE) of Human ENOX2 (NP_006366).

  • Positive control
    • U937 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferConstituents: PBS, 2% Sucrose
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab112085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 70 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
  • Tissue specificityFound in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Found on the cell borders of renal, kidney and ovarian carcinomas but not on the borders of surrounding non-cancerous stromal cells.
  • Sequence similaritiesBelongs to the ENOX family.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationCell membrane. Secreted > extracellular space. Extracellular and plasma membrane-associated.
  • Information by UniProt
  • Database links
  • Alternative names
    • APK1 antibody
    • APK1 antigen antibody
    • COVA1 antibody
    • Cytosolic ovarian carcinoma antigen 1 antibody
    • Ecto NOX disulfide thiol exchanger 2 antibody
    • ENOX 2 antibody
    • ENOX2 antibody
    • ENOX2_HUMAN antibody
    • OTTHUMP00000024021 antibody
    • OTTHUMP00000024022 antibody
    • Protein disulfide-thiol oxidoreductase antibody
    • tNOX antibody
    • Tumor associated hydroquinone oxidase antibody
    • Tumor-associated hydroquinone oxidase antibody
    see all

Anti-ENOX2 antibody images

  • Anti-ENOX2 antibody (ab112085) at 1 µg/ml + U937 cell lysate at 10 µg

    Predicted band size : 70 kDa

References for Anti-ENOX2 antibody (ab112085)

ab112085 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"