Overview

  • Product nameAnti-ENPP7 antibody
    See all ENPP7 primary antibodies
  • Description
    Rabbit polyclonal to ENPP7
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: LEVEPFESVH VYELMCRLLG IVPEANDGHL ATLLPMLHTE SALPPDGRPT LLPKGRSALP PSSRPLLVMG LLGTVILLSE, corresponding to amino acids 377-456 of Human ENPP7 (UniProt ID: Q6UWV6).

  • Positive control
    • Human colon tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionConverts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
  • Tissue specificityDetected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
  • Sequence similaritiesBelongs to the nucleotide pyrophosphatase/phosphodiesterase family.
  • Post-translational
    modifications
    N-glycosylated; required for activity and transport to the plasma membrane.
  • Cellular localizationMembrane. Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALK SMase antibody
    • Alk-SMase antibody
    • Alkaline sphingomyelin phosphodiesterase antibody
    • E-NPP 7 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase 7 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 antibody
    • ENPP7 antibody
    • ENPP7_HUMAN antibody
    • Intestinal alkaline sphingomyelinase antibody
    • NPP-7 antibody
    see all

Anti-ENPP7 antibody images

  • ab121827, at a 1/40 dilution, staining ENPP7 in paraffin embedded Human colon tissue by Immunohistochemistry.

References for Anti-ENPP7 antibody (ab121827)

ab121827 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121827.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"