Overview

  • Product nameAnti-Enterokinase antibody
    See all Enterokinase primary antibodies
  • Description
    Mouse monoclonal to Enterokinase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 361-471 of Human Enterokinase

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab55621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionResponsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
    • Tissue specificityIntestinal brush border.
    • Involvement in diseaseDefects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.
    • Sequence similaritiesBelongs to the peptidase S1 family.
      Contains 2 CUB domains.
      Contains 2 LDL-receptor class A domains.
      Contains 1 MAM domain.
      Contains 1 peptidase S1 domain.
      Contains 1 SEA domain.
      Contains 1 SRCR domain.
    • Post-translational
      modifications
      The chains are derived from a single precursor that is cleaved by a trypsin-like protease.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • PRSS 7 antibody
      • PRSS7 antibody
      • Enterokinase antibody
      • Enterokinase catalytic subunit antibody
      • Enteropeptidase antibody
      • Enteropeptidase catalytic light chain antibody
      • Enteropeptidase non catalytic heavy chain antibody
      • ENTK antibody
      • ENTK_HUMAN antibody
      • PROENTEROKINASE antibody
      • protease, serine, 7 (enterokinase) antibody
      • PRSS7 antibody
      • Serine protease 7 antibody
      • TMPRSS15 antibody
      • Transmembrane protease serine 15 antibody
      see all

    Anti-Enterokinase antibody images

    • Western blot against tagged recombinant protein immunogen using ab55621 Enterokinase antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    References for Anti-Enterokinase antibody (ab55621)

    ab55621 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab55621.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"