Anti-Enterokinase antibody [MM0259- 8S12] (ab89458)

Overview

  • Product nameAnti-Enterokinase antibody [MM0259- 8S12]
    See all Enterokinase primary antibodies
  • Description
    Mouse monoclonal [MM0259- 8S12] to Enterokinase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Human Enterokinase.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesIgG fraction of culture supernatant purified by Protein G affinity chromatography and 0.2 µm filtered.
  • ClonalityMonoclonal
  • Clone numberMM0259- 8S12
  • IsotypeIgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 113 kDa.

Target

  • FunctionResponsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
  • Tissue specificityIntestinal brush border.
  • Involvement in diseaseDefects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 2 LDL-receptor class A domains.
    Contains 1 MAM domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SEA domain.
    Contains 1 SRCR domain.
  • Post-translational
    modifications
    The chains are derived from a single precursor that is cleaved by a trypsin-like protease.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • PRSS 7 antibody
    • PRSS7 antibody
    • Enterokinase antibody
    • Enterokinase catalytic subunit antibody
    • Enteropeptidase antibody
    • Enteropeptidase catalytic light chain antibody
    • Enteropeptidase non catalytic heavy chain antibody
    • ENTK antibody
    • ENTK_HUMAN antibody
    • PROENTEROKINASE antibody
    • protease, serine, 7 (enterokinase) antibody
    • PRSS7 antibody
    • Serine protease 7 antibody
    • TMPRSS15 antibody
    • Transmembrane protease serine 15 antibody
    see all

References for Anti-Enterokinase antibody [MM0259- 8S12] (ab89458)

ab89458 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"