Overview

  • Product nameAnti-ENTPD5 antibody
    See all ENTPD5 primary antibodies
  • Description
    Rabbit polyclonal to ENTPD5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 - 161 of Human ENTPD5 (NP_001240)

  • Positive control
    • 293T, A431, H1299, HeLa and HepG2 cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.

Target

  • FunctionUridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
  • Tissue specificityExpressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
  • PathwayProtein modification; protein glycosylation.
  • Sequence similaritiesBelongs to the GDA1/CD39 NTPase family.
  • Post-translational
    modifications
    N-glycosylated; high-mannose type.
  • Cellular localizationEndoplasmic reticulum lumen.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD39 like 4 antibody
    • AI196558 antibody
    • AI987697 antibody
    • CD39 antigen like 4 antibody
    • CD39 antigen-like 4 antibody
    • CD39 like 4 antibody
    • CD39L4 antibody
    • Ectonucleoside triphosphate diphosphohydrolase 5 antibody
    • ENTP5_HUMAN antibody
    • Entpd5 antibody
    • ER UDPase antibody
    • ER-UDPase antibody
    • GDPase ENTPD5 antibody
    • Guanosine-diphosphatase ENTPD5 antibody
    • MGC163357 antibody
    • MGC163359 antibody
    • mNTPase antibody
    • NTPDase 5 antibody
    • Nucleoside diphosphatase antibody
    • PCPH antibody
    • Pcph proto oncogene protein antibody
    • Proto oncogene CPH antibody
    • UDPase ENTPD5 antibody
    • Uridine-diphosphatase ENTPD5 antibody
    see all

Anti-ENTPD5 antibody images

  • All lanes : Anti-ENTPD5 antibody (ab96067) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa

References for Anti-ENTPD5 antibody (ab96067)

ab96067 has not yet been referenced specifically in any publications.

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