Overview

  • Product name
    Eosin Y
  • Description
    Brominated fluoroscein dye derivative used as an acidic red stain for cell cytoplasm.
  • Alternative names
    • Acid Red 87
    • Bromo acid J
    • Bromofluorescein
    • Bronze Bromo ES
    • Eosin yellowish
    • Solvent red 43
    see all
  • Biological description

    A red fluorescent dye from the xanthene family used as an acidic red stain for cell cytoplasm. Reduces the affinity of Mg2+-ATPase for ATP and increases the enzyme affinity for Mg2+ at concentrations of 10-50 μM. At higher concentrations near 100 μM the affinity for Mg2+-ATPase for the ion-activator has been shown to be reduced.

Properties

  • Molecular weight
    647.90
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C20H8O5Br4
  • CAS Number
    15086-94-9
  • Storage instructions
    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in ethanol to 1 mg/ml
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Artym VV  et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol 208:331-50 (2015). Read more (PubMed: 25646088) »
  • Li T  et al. Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasis. Oncogene 33:4746-55 (2014). Read more (PubMed: 24096480) »
  • Lee SH  et al. Eosin Y-sensitized artificial photosynthesis by highly efficient visible-light-driven regeneration of nicotinamide cofactor. Chembiochem 10:1621-4 (2009). Read more (PubMed: 19551795) »
  • Gerasimova MA  et al. The role of energy transfer in bioluminescence quenching by xanthene dyes. J Photochem Photobiol B 97:117-22 (2009). Read more (PubMed: 19864157) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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