Recombinant
RabMAb

Anti-Eotaxin antibody [EPR5824] (ab125018)

Overview

  • Product name
    Anti-Eotaxin antibody [EPR5824]
    See all Eotaxin primary antibodies
  • Description
    Rabbit monoclonal [EPR5824] to Eotaxin
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human Eotaxin.

  • Positive control
    • Eotaxin recombinant protein.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Dissociation constant (KD)
    KD = 8.80 x 10 -11 M
    Learn more about KD
  • Storage buffer
    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR5824
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab125018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 8 kDa (predicted molecular weight: 11 kDa). Tested using the recombinant protein.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications
      O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C-C motif chemokine 11 antibody
      • CCL 11 antibody
      • CCL11 antibody
      • CCL11_HUMAN antibody
      • chemokine (C-C motif) ligand 11 antibody
      • Chemokine C C motif ligand 11 antibody
      • Chemokine CC Motif Ligand 11 antibody
      • Chemokine ligand 11 antibody
      • Eosinophil chemotactic protein antibody
      • Eotaxin antibody
      • eotaxin-1 antibody
      • MGC22554 antibody
      • SCYA 11 antibody
      • SCYA11 antibody
      • Small inducible cytokine A11 antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 11 antibody
      • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody
      • Small inducible cytokine subfamily A member 11 antibody
      • Small-inducible cytokine A11 antibody
      see all

    Images

    • Anti-Eotaxin antibody [EPR5824] (ab125018) at 1/1000 dilution + Eotaxin recombinant protein at 0.01 µg

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 11 kDa
      Observed band size : 8 kDa (why is the actual band size different from the predicted?)
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab125018 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab125018.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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