Overview

  • Product nameAnti-EPC1 antibody
    See all EPC1 primary antibodies
  • Description
    Rabbit polyclonal to EPC1
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 325-375 of Human EPC1 (NP_079485.1).

  • Positive control
    • HeLa whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab112043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 93 kDa.
IP Use at 2-10 µg/mg of lysate.

Target

  • FunctionComponent of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
  • Sequence similaritiesBelongs to the enhancer of polycomb family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp781P2312 antibody
    • Enhancer of polycomb 1 antibody
    • Enhancer of polycomb homolog 1 (Drosophila) antibody
    • Enhancer of polycomb homolog 1 antibody
    • EPC1 antibody
    • EPC1_HUMAN antibody
    • Epl 1 antibody
    • Epl1 antibody
    • OTTHUMP00000046260 antibody
    see all

Anti-EPC1 antibody images

  • All lanes : Anti-EPC1 antibody (ab112043) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    Developed using the ECL technique

    Predicted band size : 93 kDa


    Exposure time : 3 minutes
  • Detection of EPC1 by Western Blot of Immunprecipitate.
    ab112043 at 1µg/ml staining EPC1 in HeLa whole cell lysate immunoprecipitated using ab112043 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 10 seconds.

References for Anti-EPC1 antibody (ab112043)

ab112043 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112043.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"