Overview

  • Product nameAnti-EPCR/CD201 antibody [RCR-379]
    See all EPCR/CD201 primary antibodies
  • Description
    Rat monoclonal [RCR-379] to EPCR/CD201
  • Tested applicationsSuitable for: IHC-Fr, Functional Studies, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tail base human EPCR positive RE1 cells

  • General notes


    ab81711 is useful for the inhibition of biological activity. The antibody inhibits thrombin dependent protein C activation and blocks APC mediated signalling.

Properties

Applications

Our Abpromise guarantee covers the use of ab81711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/10 - 1/50.
Functional Studies 1/5 - 1/50.
Flow Cyt 1/10 - 1/50. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • FunctionBinds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
  • Tissue specificityExpressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
  • Post-translational
    modifications
    N-glycosylated.
    A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activated protein C receptor antibody
    • APC receptor antibody
    • APCR antibody
    • bA42O4.2 antibody
    • CCCA antibody
    • CCD41 antibody
    • CD201 antibody
    • CD201 antigen antibody
    • cell cycle, centrosome-associated protein antibody
    • Cell cycle, centrosome-associated protein antibody
    • centrocyclin antibody
    • Endothelial cell protein C receptor antibody
    • Endothelial protein C receptor antibody
    • EPCR antibody
    • EPCR_HUMAN antibody
    • MGC23024 antibody
    • PROCR antibody
    • Protein C receptor, endothelial antibody
    see all

References for Anti-EPCR/CD201 antibody [RCR-379] (ab81711)

This product has been referenced in:
  • Navarro S  et al. Association of the Thrombomodulin Gene c.1418C>T Polymorphism With Thrombomodulin Levels and With Venous Thrombosis Risk. Arterioscler Thromb Vasc Biol N/A:N/A (2013). Blocking ; Human . Read more (PubMed: 23520161) »

See 1 Publication for this product

Product Wall

Thanks for your email. I'm very sorry that even the replacement antibody still does not appear to be working as expected.

To help improve your results, Iam happy to provide a replacement of any primary antibody, credit or refund. Please let m...

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Thank you very much for your interest in ab81711. FuncS refers to this antibody's ability to inhibit the biological activity of EPCR. Unfortunately, all of the data we have for this clone is currently available on the online datasheet.

Becau...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"