Anti-EPH A3+A4+A5 (phospho Y779) antibody (ab111407)


  • Product nameAnti-EPH A3+A4+A5 (phospho Y779) antibody
    See all EPH A3+A4+A5 primary antibodies
  • Description
    Rabbit polyclonal to EPH A3+A4+A5 (phospho Y779)
  • SpecificityThis antibody detects endogenous levels of EPH A3 + A4 + A5 only when phosphorylated at tyrosine 779.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from Human EPH A3+A4+A5 around the phosphorylation site of tyrosine 779 (A-A-YP-T-T).

  • Positive control
    • Human brain tissue


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab111407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • RelevanceReceptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal andhippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. Beside its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.
  • Cellular localizationCell Membrane
  • Database links
  • Alternative names
    • CEK7 antibody
    • EHK 1 antibody
    • EHK1 antibody
    • EK4 antibody
    • EK7 antibody
    • EK8 antibody
    • EPH homology kinase 1 antibody
    • EPH like kinase 4 antibody
    • EPH like kinase 7 antibody
    • EPH like kinase 8 antibody
    • Eph like tyrosine kinase 1 antibody
    • EPH receptor A3 antibody
    • EPH receptor A4 antibody
    • EPH receptor A5 antibody
    • EPHA3 antibody
    • EPHA4 antibody
    • EPHA5 antibody
    • Ephrin type A receptor 3 antibody
    • Ephrin type A receptor 4 antibody
    • Ephrin type A receptor 5 antibody
    • ETK antibody
    • ETK1 antibody
    • HEK antibody
    • HEK4 antibody
    • HEK7 antibody
    • HEK8 antibody
    • Human embryo kinase 1 antibody
    • OTTHUMP00000159594 antibody
    • OTTHUMP00000159595 antibody
    • OTTHUMP00000164185 antibody
    • OTTHUMP00000204491 antibody
    • OTTHUMP00000213903 antibody
    • OTTHUMP00000213904 antibody
    • OTTHUMP00000213905 antibody
    • OTTHUMP00000218917 antibody
    • OTTHUMP00000223029 antibody
    • Receptor protein tyrosine kinase HEK7 antibody
    • Receptor protein tyrosine kinase HEK8 antibody
    • SEK antibody
    • TYRO1 antibody
    • TYRO1 protein tyrosine kinase antibody
    • TYRO4 antibody
    • TYRO4 protein tyrosine kinase antibody
    • Tyrosine protein kinase receptor EHK 1 antibody
    • Tyrosine protein kinase receptor ETK1 antibody
    • Tyrosine protein kinase receptor SEK antibody
    • Tyrosine protein kinase TYRO1 antibody
    see all

Anti-EPH A3+A4+A5 (phospho Y779) antibody images

  • ab111407 at 1/50 dilution staining EPH A3+A4+A5 (phospho Y779) in paraffin-embedded Human brain tissue by Immunohistochemistry. The image on the right is treated with synthesized phosphopeptide.

References for Anti-EPH A3+A4+A5 (phospho Y779) antibody (ab111407)

ab111407 has not yet been referenced specifically in any publications.

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