• Product nameAnti-Eph receptor A1 antibody
    See all Eph receptor A1 primary antibodies
  • Description
    Rabbit polyclonal to Eph receptor A1
  • SpecificityThis antibody detects endogenous levels of total Eph receptor A1 protein.
  • Tested applicationsSuitable for: WB, ICC/IF, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) from an internal region of Eph receptor A1.

  • Positive control
    • WB: Extracts from COLO205 cells. ICC/IF: HeLa cells.



Our Abpromise guarantee covers the use of ab65074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 108 kDa).
ICC/IF 1/500 - 1/1000.
ELISA 1/10000.


  • FunctionReceptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
  • Tissue specificityOverexpressed in several carcinomas.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 1 Eph LBD (Eph ligand-binding) domain.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Post-translational
    Phosphorylated. Autophosphorylation is stimulated by its ligand EFNA1.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EPH antibody
    • EPH receptor A1 antibody
    • EPH tyrosine kinase 1 antibody
    • EPH tyrosine kinase antibody
    • Epha1 antibody
    • EPHA1_HUMAN antibody
    • Ephrin receptor Eph A1 antibody
    • Ephrin type A receptor 1 antibody
    • Ephrin type-A receptor 1 antibody
    • EPHT 1 antibody
    • EPHT antibody
    • EPHT1 antibody
    • Erythropoietin producing hepatoma amplified sequence antibody
    • Erythropoietin-producing hepatoma receptor antibody
    • Esk antibody
    • hEpha1 antibody
    • MGC163163 antibody
    • Oncogene EPH antibody
    • Soluble EPHA1 variant 1 antibody
    • Soluble EPHA1 variant 2 antibody
    • Tyrosine protein kinase receptor EPH antibody
    • Tyrosine-protein kinase receptor EPH antibody
    see all

Anti-Eph receptor A1 antibody images

  • All lanes : Anti-Eph receptor A1 antibody (ab65074) at 1/500 dilution

    Lane 1 : Extracts from COLO205 cells
    Lane 2 : Extracts from COLO205 cells with blocking peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 108 kDa
    Observed band size : 108 kDa
  • Immunofluorescence analysis of HeLa cells ab65074 (1/50).

    The left panel is in the absence of blocking peptide, whereas the right panel is in the presence of blocking peptide.

References for Anti-Eph receptor A1 antibody (ab65074)

ab65074 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65074.
Please use the links above to contact us or submit feedback about this product.