Overview

  • Product name
    Anti-Eph receptor A4 antibody [M280]
    See all Eph receptor A4 primary antibodies
  • Description
    Mouse monoclonal [M280] to Eph receptor A4
  • Host species
    Mouse
  • Specificity
    The region used as immunogen has less than 50% homology with other EphA and EphB family members.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken
  • Immunogen

    Recombinant fragment corresponding to amino acids in the N terminal region of Human Eph receptor A4.

  • Positive control
    • HUVEC and Mouse brain tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab157588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 95, 120 kDa (predicted molecular weight: 110 kDa).

Target

  • Function
    Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Domain
    The protein kinase domain mediates interaction with NGEF/ephexin-1.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cek 8 antibody
    • CEK8 antibody
    • EK8 antibody
    • eph receptor a4 antibody
    • EPH-like kinase 8 antibody
    • EPHA4 antibody
    • EPHA4_HUMAN antibody
    • Ephrin type-A receptor 4 antibody
    • HEK 8 antibody
    • hEK8 antibody
    • Receptor protein-tyrosine kinase HEK8 antibody
    • Sek 1 antibody
    • SEK antibody
    • TYRO 1 protein tyrosine kinase antibody
    • TYRO1 antibody
    • Tyrosine-protein kinase receptor SEK antibody
    • Tyrosine-protein kinase TYRO1 antibody
    see all

Images

  • All lanes : Anti-Eph receptor A4 antibody [M280] (ab157588) at 1/1000 dilution

    Lane 1 : HUVEC cells
    Lane 2 : HUVEC cells treated with
    pervanadate (1 mM) for 30 min

    Predicted band size: 110 kDa

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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