Anti-Eph receptor B1 + Eph receptor B2 antibody (ab61765)

Overview

  • Product name
    Anti-Eph receptor B1 + Eph receptor B2 antibody
    See all Eph receptor B1 + Eph receptor B2 primary antibodies
  • Description
    Rabbit polyclonal to Eph receptor B1 + Eph receptor B2
  • Tested applications
    Suitable for: ELISA, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human Eph receptor B1 from around the phosphorylation site of tyrosine 594 (K-I-YP-I-D).

  • Positive control
    • Extracts from HepG2 cells, HuvEc cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab61765 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 110 kDa).
ICC/IF 1/500 - 1/1000.

Target

  • Relevance
    Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
  • Cellular localization
    Membrane; Single-pass type I membrane protein.
  • Database links
  • Alternative names
    • EPH B1 antibody
    • EPH B2 antibody
    • Eph tyrosine kinase 2 antibody
    • Eph tyrosine kinase 3 antibody
    • EPHB1 antibody
    • EPHB2 antibody
    • Ephrin receptor EphB1 antibody
    • Ephrin receptor EphB2 antibody
    • Ephrin type B receptor 1 antibody
    • Ephrin type B receptor 2 antibody
    • EPHT 2 antibody
    • EPHT 3 antibody
    • ERK antibody
    • Hek 5 antibody
    • Hek 6 antibody
    • Tyrosine protein kinase receptor EPH2 antibody
    • Tyrosine protein kinase receptor EPH3 antibody
    see all

Images

  • HuvEc cells stained wth ab61765 at 1/500 - 1/1000, with and without the immunising peptide.
  • All lanes : Anti-Eph receptor B1 + Eph receptor B2 antibody (ab61765) at 1/500 dilution

    Lane 1 : Extracts from HepG2 cells.
    Lane 2 : Extracts from HepG2 cells and the immunising peptide.


    Predicted band size : 110 kDa
    Observed band size : 110 kDa
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHB1/2 Antibody. The picture on the right is blocked with the synthesized peptide.

References

ab61765 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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