Overview

  • Product name
    Anti-Eph receptor B3 antibody
    See all Eph receptor B3 primary antibodies
  • Description
    Goat polyclonal to Eph receptor B3
  • Specificity
    The antibody shows less than 5% cross-reactivity with recombinant rat EphB1, recombinant mouse EphB2, and recombinant mouse EphB6.
  • Tested applications
    Suitable for: IHC-Fr, ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Purified recombinant mouse EphB3 extracellular domain expressed mouse NSO cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab10617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent dilution. PubMed: 20496368
ELISA Use a concentration of 0.5 - 1 µg/ml. The detection limit for recombinant mouse EphB3 is approx. 0.6 ng/well.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 82 kDa. The detection limit for recombinant mouse EphB3 is approximately 5 ng/lane and 1 ng/lane under non-reducing and reducing conditions, respectively. As a result of glycosylation, recombinant EphB3/Fc migrates as an approximately 100 kDa protein under reducing conditions in SDS-PAGE.

Target

  • Function
    Receptor for members of the ephrin-B family. Binds to ephrin-B1 and -B2.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cek10 antibody
    • EK2 antibody
    • Embryonic kinase 2 antibody
    • EPH Like Tyrosine Kinase 2 antibody
    • EPH receptor B3 antibody
    • EPH-like kinase 2 antibody
    • ephb3 antibody
    • EPHB3_HUMAN antibody
    • Ephrin receptor EphB3 antibody
    • Ephrin type B receptor 3 antibody
    • Ephrin type-B receptor 3 antibody
    • ETK2 antibody
    • hEK2 antibody
    • Human Embryo Kinase 2 antibody
    • Mdk5 antibody
    • Sek4 antibody
    • TYRO6 antibody
    • Tyrosine protein kinase receptor HEK2 antibody
    • Tyrosine protein kinase TYRO6 antibody
    • Tyrosine-protein kinase TYRO6 antibody
    see all

References

This product has been referenced in:
  • Theus MH  et al. EphB3 Limits the Expansion of Neural Progenitor Cells in the Subventricular Zone by Regulating p53 During Homeostasis and Following Traumatic Brain Injury. Stem Cells 28:1231-42 (2010). WB, IHC-Fr ; Mouse . Read more (PubMed: 20496368) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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