Overview

  • Product nameAnti-Ephrin B1 antibody
    See all Ephrin B1 primary antibodies
  • Description
    Rabbit polyclonal to Ephrin B1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 179-228 (SRPSKEADNT VKMATQAPGS RGSLGDSDGK HETVNQEEKS GPGASGGSSG) of Human Ephrin B1 (NP_004420).

  • Positive control
    • Human fetal kidney lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionBinds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
  • Tissue specificityHeart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
  • Involvement in diseaseDefects in EFNB1 are a cause of craniofrontonasal syndrome (CFNS) [MIM:304110]; also known as craniofrontonasal dysplasia (CFND). CFNS is an X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies.
  • Sequence similaritiesBelongs to the ephrin family.
  • Post-translational
    modifications
    Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CFND antibody
    • CFNS antibody
    • Craniofrontonasal syndrome (craniofrontonasal dysplasia) antibody
    • EFL 3 antibody
    • EFL-3 antibody
    • EFL3 antibody
    • EFNB1 antibody
    • EFNB1_HUMAN antibody
    • Elk L antibody
    • ELK ligand antibody
    • ELK-L antibody
    • Eph related receptor tyrosine kinase ligand 2 antibody
    • EPH-related receptor tyrosine kinase ligand 2 antibody
    • Ephrin-B1 antibody
    • EPLG2 antibody
    • LERK 2 antibody
    • LERK-2 antibody
    • LERK2 antibody
    • Ligand of eph related kinase 2 antibody
    • MGC8782 antibody
    see all

Anti-Ephrin B1 antibody images

  • Anti-Ephrin B1 antibody (ab99029) at 1 µg/ml + Human fetal kidney lysate at 10 µg
    Developed using the ECL technique

    Predicted band size : 38 kDa

References for Anti-Ephrin B1 antibody (ab99029)

ab99029 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99029.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"