Overview

  • Product name
  • Description
    Rabbit polyclonal to EPHX2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH-conjugated synthetic peptide from an internal domain of Human EPHX2

  • Positive control
    • Human kidney tissue

Applications

Our Abpromise guarantee covers the use of ab115284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Has low phosphatase activity.
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
  • Domain
    The N-terminal domain has phosphatase activity. The C-terminal domain has epoxide hydrolase activity.
  • Post-translational
    modifications
    The N-terminus is blocked.
    The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation.
  • Cellular localization
    Cytoplasm. Peroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bifunctional epoxide hydrolase 2 antibody
    • CEH antibody
    • Cytosolic epoxide hydrolase antibody
    • EPHX2 antibody
    • Epoxide hydratase antibody
    • Epoxide hydrolase 2 antibody
    • Epoxide hydrolase 2 cytoplasmic antibody
    • epoxide hydrolase 2, cytosolic antibody
    • Epoxide hydrolase soluble antibody
    • HYES_HUMAN antibody
    • SEH antibody
    • Soluble epoxide hydrolase antibody
    see all

Images

  • Human kidney formalin-fixed, paraffin-embedded tissue stained with ab115284 at 20 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115284 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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