The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Predicted molecular weight: 68 kDa.
RelevanceEPN3 belongs to the epsin family. It is detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. It is detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
Cellular localizationCytoplasm. Cytoplasm; perinuclear region. Cytoplasmic vesicle; clathrin-coated vesicle. Nucleus. Note: Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.