Overview

  • Product nameAnti-Epoxide hydrolase antibody
    See all Epoxide hydrolase primary antibodies
  • Description
    Rabbit polyclonal to Epoxide hydrolase
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Pig
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 64 and 262 of human Epoxide hydrolase (NP_000111)

  • Positive control
    • 293T, H1299 and HeLa cells. SG xenograft.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab96774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

Target

  • FunctionBiotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
  • Tissue specificityFound in liver.
  • Involvement in diseaseNote=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls.
    Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.
  • Sequence similaritiesBelongs to the peptidase S33 family.
  • Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EPHX 1 antibody
    • EPHX antibody
    • Ephx1 antibody
    • EPOX antibody
    • Epoxide hydratase antibody
    • Epoxide hydrolase 1 antibody
    • Epoxide hydrolase 1 microsomal (xenobiotic) antibody
    • Epoxide hydroxylase 1 antibody
    • Epoxide hydroxylase 1 microsomal (xenobiotic) antibody
    • HYEP_HUMAN antibody
    • HYL1 antibody
    • MEH antibody
    • Microsomal epoxide hydrolase antibody
    see all

Anti-Epoxide hydrolase antibody images

  • All lanes : Anti-Epoxide hydrolase antibody (ab96774) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 53 kDa
  • Immunohistochemical analysis of paraffin-embedded SG xenograft, using ab96774 at 1/100 dilution.
  • Immunofluorescence analysis of methanol fixed HeLa, using ab96774 at 1/200 dilution (top image) and costained with Hoescht 33342 (bottom image).

References for Anti-Epoxide hydrolase antibody (ab96774)

ab96774 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"