Anti-EPS15R antibody - Aminoterminal end (ab71728)

Overview

  • Product nameAnti-EPS15R antibody - Aminoterminal end
    See all EPS15R primary antibodies
  • Description
    Rabbit polyclonal to EPS15R - Aminoterminal end
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the N terminal region of human EPS15R.

  • Positive control
    • Y79 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab71728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 104 kDa (predicted molecular weight: 94 kDa).

Target

  • FunctionSeems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
  • Sequence similaritiesContains 1 EF-hand domain.
    Contains 3 EH domains.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues by EGFR.
  • Cellular localizationCell membrane. Nucleus. Membrane > coated pit. Localized to plasma membrane coated pits.
  • Information by UniProt
  • Database links
  • Alternative names
    • EP15R_HUMAN antibody
    • epidermal growth factor receptor pathway substrate 15- ike 1 antibody
    • Epidermal growth factor receptor substrate 15 like 1 antibody
    • Epidermal growth factor receptor substrate 15-like 1 antibody
    • epidermal growth factor receptor substrate EPS15R antibody
    • Eps15 related protein antibody
    • Eps15-related protein antibody
    • EPS15L1 antibody
    • Eps15R antibody
    see all

Anti-EPS15R antibody - Aminoterminal end images

  • Anti-EPS15R antibody - Aminoterminal end (ab71728) at 1/100 dilution + Y79 cell lysate at 12.5 µg

    Predicted band size : 94 kDa
    Observed band size : 104 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa,50 kDa. We are unsure as to the identity of these extra bands.

References for Anti-EPS15R antibody - Aminoterminal end (ab71728)

ab71728 has not yet been referenced specifically in any publications.

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