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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 1% BSA, 1X PBS, pH 7
Concentration information loading...
Purity Immunogen affinity purified
Purification notes Purified by antigen affinity chromatography.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 92 kDa.
1/100 - 1/250.
Function Upon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
Tissue specificity Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
Sequence similarities Belongs to the EPS8 family. Contains 1 PH domain. Contains 1 SH3 domain.
Domain The SH3 domain mediates interaction with SHB.
Post-translational modifications Phosphorylated by several receptor tyrosine kinases.
Information by UniProt
Epidermal growth factor receptor kinase substrate 8 antibody
Epidermal growth factor receptor pathway substrate 8 antibody
EPS 8 antibody
Anti-EPS8 antibody images
Western blot - EPS8 antibody (ab96144)
All lanes : Anti-EPS8 antibody (ab96144) at 1/1000 dilution Lane 1 : H1299 whole cell lysate Lane 2 : Hela whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 92 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - EPS8 antibody (ab96144)
ab96144, at 1/100 dilution, staining EPS8 in paraffin embedded Gastric CA by Immunohistochemical analysis.
References for Anti-EPS8 antibody (ab96144)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"