Overview

  • Product nameAnti-EREG antibody [MM0265- 12Y4]
    See all EREG primary antibodies
  • Description
    Mouse monoclonal [MM0265- 12Y4] to EREG
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human EREG protein.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
  • ClonalityMonoclonal
  • Clone numberMM0265- 12Y4
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 19 kDa.

Target

  • FunctionMay be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.
  • Tissue specificityIn normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.
  • Sequence similaritiesContains 1 EGF-like domain.
  • Cellular localizationCell membrane and Secreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • Epiregulin antibody
    • EPR antibody
    • ER antibody
    • Ereg antibody
    • EREG_HUMAN antibody
    • Proepiregulin antibody
    see all

References for Anti-EREG antibody [MM0265- 12Y4] (ab89291)

This product has been referenced in:
  • Oliveras-Ferraros C  et al. Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells. Br J Cancer 106:1406-14 (2012). Read more (PubMed: 22491422) »

See 1 Publication for this product

Product Wall

Thank you for your reply. If the white band you are seeing on the darker background is at a molecular weight of 19 kDa, then it is the specific band of interest. The band can show up lighter than the background when the signal is too strong and the ECL...

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Thank you for contacting us. I am sorry this antibody is not giving good results in WB. Can you please provide some additional details of your experiment?

1) What type of samples were you testing and how were they prepared (lysis buffer, prot...

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Thank you for contacting us and your interest in our products. We have several antibodies directed against amphiregulin and epiregulin, however, as discussed over the phone, none have as yet been tested in IHC.

This does not mean that they wo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"