Overview

  • Product name
  • Description
    Rabbit polyclonal to eRF3B/GSPT2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a regionn within internal sequence amino acids 223-253 of Human eRF3B/GSPT2

  • Positive control
    • 293 cell line lysates; Mouse spleen tissue lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab103005 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 69 kDa.

Target

  • Function
    Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
  • Tissue specificity
    Highly expressed in IUCC stage II colorectal cancer (CRC).
  • Sequence similarities
    Belongs to the GTP-binding elongation factor family. ERF3 subfamily.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • eRF3b antibody
    • ERF3B_HUMAN antibody
    • Eukaryotic peptide chain release factor GTP-binding subunit ERF3B antibody
    • Eukaryotic peptide chain release factor subunit 3b antibody
    • G1 to S phase transition 2 antibody
    • G1 to S phase transition protein 2 homolog antibody
    • Gspt2 antibody
    • GST2 antibody
    • peptide chain release factor 3 antibody
    see all

Images

  • Anti-eRF3B/GSPT2 antibody (ab103005) at 1/100 dilution + 293 cell line lysates at 35 µg

    Predicted band size : 69 kDa
  • Anti-eRF3B/GSPT2 antibody (ab103005) at 1/100 dilution + Mouse spleen tissue lysate at 35 µg

    Predicted band size : 69 kDa

References

ab103005 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab103005.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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