Overview

  • Product name
  • Description
    Goat polyclonal to ERLIN1
  • Specificity
    Reported variants represent identical protein: NP_006450.2, NP_001094096.1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog, Pig, Chimpanzee, Macaque monkey, Orangutan
  • Immunogen

    Synthetic peptide corresponding to C terminal amino acids 331-345 (

    EALEPSGENVIQNKE

    ) by a Cysteine residue linker of human ERLIN1 (NP_006450.2)

  • Positive control
    • Human placenta lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab90427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).

Target

  • Function
    Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs).
  • Tissue specificity
    Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
  • Sequence similarities
    Belongs to the band 7/mec-2 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Band 7 23-211 Keo4 (Interim) similar to C.elegans protein antibody
    • C10orf69 antibody
    • chromosome 10 open reading frame 69 antibody
    • Endoplasmic reticulum lipid raft-associated protein 1 antibody
    • ER lipid raft associated 1 antibody
    • Erlin 1 antibody
    • Erlin-1 antibody
    • ERLIN1 antibody
    • ERLN1_HUMAN antibody
    • KE04 antibody
    • KEO4 antibody
    • OTTHUMP00000059425 antibody
    • Protein KE04 antibody
    • SPFH domain containing protein 1 antibody
    • SPFH domain family, member 1 antibody
    • SPFH domain-containing protein 1 antibody
    • SPFH1 antibody
    • SPG62 antibody
    • Stomatin-prohibitin-flotillin-HflC/K domain containing protein 1 antibody
    • Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 antibody
    see all

Images

  • Anti-ERLIN1 antibody (ab90427) at 0.5 µg/ml + Human placenta lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 39 kDa

References

ab90427 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab90427.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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